Organised on a monthly basis, the cafés constitutes an informal get-together for the ICM Neuroinformatics community.

The many themes & issues around Data Science and Neuroinformatics are addressed and it is a time for sharing and informing. You will find below the themes presented since 2018.

Upcoming café

Atlas YEB WEB
28 November 2019, Jordan Cornillault (CENIR)

Previous cafés

Computational Pathology: a path ahead
19 September 2019, Daniel Racoceanu (Hassan Lab)

Anatomic pathology represents an essential referential examination in medicine. The evolution of slide scanning currently allows for more ergonomic work on virtual slides, leading to the so-called Digital Pathology.

Beyond the challenges generated by this technology (adaptation of the diagnosis protocol, high-resolution / high-content images, fluidity of online examination / streaming, significant storage resources, control of data security), this represents a real clinical and medical / scientific research opportunity.

The spectacular development of high-content image analysis techniques, as well as deep learning, generates an increasing interest in Computational Pathology, particularly through its integrative aspects (Integrative Digital Pathology), a strategic link between clinic, pathology and molecular biology.

In this talk, we wish to introduce some of the recently developments in the field of tumor environment analysis, tumor heterogeneity and the simulation through the prism of Digital Patology. Even if presented in the cancer context, these technologies could be of a great use for a series of pathologies.

Replay

Introduction to OMERO
11 July 2019, Nabila Elarouci (Centre for Neuroinformatics)

OME Remote Objects (OMERO) is a client-server software platform for visualizing, managing, and annotating scientific image data. Using the power of Bio-Formats, OMERO supports over 140 image file formats, including all major microscope formats.

The Centre for Neuroinformatics and the ICM microscopy imaging facilities have been testing Omero, it will help the teams to manage all  images using a secure central repository, from the microscope to publications. 

Replay

Ontological model to integrate of heterogeneous omic data

13 June 2019, Vincent Henry (AramisLab)

The combination of ontology and systems engineering provides a consistent and formal network of classes with an appropriate granularity to integrate heterogeneous multi-omic data related to molecular physiopathology; a use case on Alzheimer Disease.

From data Quality Control to quantitative Magnetic Resonance, the big data perspective.

16 May 2019, Romain Valabregue (CENIR)

Quality Control (QC) is often presented as the first necessary step for big data analysis. Here we are interested by the opportunity to use big data analysis in order to derive quantitative QC metrics that will allow the estimate of the bias and the error on computed IDP: Image Derived Phenotype

For anatomical T1 images, IDP are volumetric measures deduce from segmentation process. The bias and the precision of those measures are dependent on

  • The acquisition parameters (hardware/sequences) that will change the SNR and the contrast.
  • The subject’s physiology which in case of pathologies will alter the contrast.
  • The data quality (physical and subjects artifacts like motion) that will change the precision.

MR technique is a very sensitive method but in counterpart less specifics. This is due to the complex interactions between the subject’s physiology and acquisition parameters where an explicit modelization is not possible. The big data approach gives the opportunity to directly estimate from the data, the factors that influence the bias and the precision of the derived IDP.

Replay

Epimicro: human intracranial EEG data storage
25 April 2019, Katia Lehongre (STIM)

Since 2010, intracranial electroencephalography recorded for clinical purposes in epileptic patients who undergo presurgical exploration, are simultaneously recorded with an amplifier dedicated to research. The recording is continuous and lasts for 2 to 3 weeks. For each patient, all  iEEG data is stored at the ICM, along with clinical information and neuroimages. Data are then accessed by research Teams that have research protocols ongoing with those patients. A graphical database to share clinical information is in progress.

Replay

A general statistical framework for data fusion

21 March 2019, Arthur Tenenhaus (CentraleSupelec/Laboratoire des Signaux et Systèmes (L2S), Paris-Saclay & iCONICS, ICM)

Challenges related to making use of the wealth data (e.g omics data, imaging-genetic data, etc…) include extracting relevant elements within massive amounts of variables, reducing dimensionality, summarizing information in a comprehensible way and displaying it for interpretation purposes. Dedicated modelling algorithms able to cope with the inherent properties of these structured datasets are therefore mandatory for harnessing their complexity and provide relevant information.

Replay

Data transfer with Globus

21 February 2019, Ludovic Prévost (IT Services)

Globus lets researchers share data on storage systems with other institutions. Globus manages access simply and securely, so researchers can focus on their work.

Replay

 

Unsupervised mapping of the vasculature from high resolution scans
January 2019, Nicolas Renier (Renier Team)

High throughput quantification of locomotor patterns in zebrafish: Motivation, Open questions, Challenges…
December 2018, Claire Wyart (Wyart Lab)

Replay

Storage overview at ICM
December 2018, Ludovic Prévost (DSI)

Brain Computer Interfaces (BCI) – What if you could write as fast as you think?
November 2018, Marie-Constance Corsi (AramisLab)

Introducing INCF, the International Neuroinformatics Coordinating Facility
September 2018, Lydia Yahia-Cherif (CENIR MEG-EEG)

 Link to INCF website

The GDPR & you – The impact on your work
July 2018, Ségolène Aymé (Emeritus Director of Research – Inserm)

Replay

4 frameworks to quickly make your code usable by biologists
June 2018, Nicolas Beaume (Eq. Ravassard) & Justine Guégan (iCONICS)

Replay Justine Guégan’s presentation

Replay Nicolas Beaume’s presentation

Processing high-throughput sequencing data with a Python workflow management system: pipelines and applications
May 2018, Justine Guégan & Damien Ulveling (iCONICS)

Replay

A web-based server for automatic analysis of EEG data. Applications for consciousness detection in brain-injured patients
April 2018, Jacobo Sitt (Cohen – Naccache – Bartolomeo team)

Clinica – a software platform for clinical neuroscience studies
April 2018, Olivier Colliot (Aramis Lab)

Replay

Bio-inspired benchmark generator for extracellular multi-unit recordings
March 2018, Sirenia Lizbeth Mondragon Gonzalez (BEBG Team)

STIM Softwares
January 2018, Sara Fernandez-Vidal (CENIR)